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Isabella Dell'Aica Selected Research

Tea

5/2007Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
12/2004Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
12/2004Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model.
7/2003Proteinase-3 directly activates MMP-2 and degrades gelatin and Matrigel; differential inhibition by (-)epigallocatechin-3-gallate.
4/2003Neutrophil restraint by green tea: inhibition of inflammation, associated angiogenesis, and pulmonary fibrosis.
12/2002(-)Epigallocatechin-3-gallate directly inhibits MT1-MMP activity, leading to accumulation of nonactivated MMP-2 at the cell surface.
7/2002Inhibition of matrix-proteases by polyphenols: chemical insights for anti-inflammatory and anti-invasion drug design.

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Isabella Dell'Aica Research Topics

Disease

8Inflammation (Inflammations)
05/2007 - 07/2002
8Neoplasms (Cancer)
05/2007 - 07/2002
4Neoplasm Metastasis (Metastasis)
05/2007 - 12/2002
3Pulmonary Fibrosis (Fibrosing Alveolitis)
05/2007 - 04/2003
2Fibrosis (Cirrhosis)
05/2007 - 04/2003
2Carcinoma (Carcinomatosis)
12/2004 - 12/2004
1Demyelinating Diseases (Demyelinating Disease)
01/2008
1Pathologic Processes
05/2007
1Adenocarcinoma
12/2004
1Prostatic Neoplasms (Prostate Cancer)
12/2004
1Anthrax
04/2004
1Pneumonia (Pneumonitis)
04/2003
1Fibrosarcoma
12/2002

Drug/Important Bio-Agent (IBA)

7TeaIBA
05/2007 - 07/2002
4hyperforinIBA
01/2008 - 09/2004
4Peptide Hydrolases (Proteases)FDA Link
05/2007 - 07/2002
3Leukocyte Elastase (Neutrophil Elastase)IBA
05/2007 - 07/2002
3progelatinaseIBA
12/2004 - 12/2002
3matrigelIBA
12/2004 - 07/2003
2PolyphenolsIBA
05/2007 - 07/2002
2GelatinasesIBA
05/2007 - 07/2002
2Serine Proteases (Serine Protease)IBA
12/2004 - 07/2003
2GelatinIBA
12/2004 - 07/2003
1Bleomycin (Blenoxane)FDA LinkGeneric
05/2007
1Antidepressive Agents (Antidepressants)IBA
05/2007
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
05/2007
1Collagen Type IV (Type IV Collagen)IBA
12/2004
1Prostate-Specific Antigen (Semenogelase)IBA
12/2004
1Glycoproteins (Glycoprotein)IBA
12/2004
1dicyclohexylamineIBA
09/2004
1SaltsIBA
09/2004
1anthrax toxin (anthrax lethal factor)IBA
04/2004
1Caseins (Casein)FDA Link
07/2003
1Extracellular Matrix ProteinsIBA
07/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2003
1ChemokinesIBA
04/2003
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
12/2002

Therapy/Procedure

1Oral Administration
04/2003